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Colon disease spectrum with normal tissue array as control, including TNM, clinical stage and pathology grade with MMR (MLH1/PMS2/MSH2/MSH6) IHC results, containing 34 cases of adenocarcinoma, 2 carcinoid, 20 metastatic carcinoma, 5 each of adenoma
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Colon cancer with adjacent normal colon tissue array, including TNM and pathology grade with MMR (MLH1/PMS2/MSH2/MSH6) IHC results, containing 140 cases of adenocarcinoma, 52 cases of mucinous adenocarcinoma and 8 adjacent normal colon tissue, 200
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Colon cancer with colon tissue array, including pathology grade, with MMR (MLH1/PMS2/MSH2/MSH6) IHC results,TNM and clinical stage, containing 86 cases of adenocarcinoma, 4 papillary adenocarcinoma, 7 mucinous adenocarcinoma, 2 adenoma, 1 congenital megacolon, 2 colon
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Image Search Results
Journal: The Journal of Experimental Medicine
Article Title: VEGFR2 induces c-Src signaling and vascular permeability in vivo via the adaptor protein TSAd
doi: 10.1084/jem.20111343
Figure Lengend Snippet: TSAd interactions with VEGFR2 and Src. (A) Immobilized peptides corresponding to tyrosine phosphorylation sites in VEGFR2 and TSAd were probed using TSAd GST-SH2 (left) or c-Src GST-SH2 (right) domain fusion proteins. The phosphotyrosine position in VEGFR2 or TSAd is indicated to the left and the peptide sequence to the right in the figure. The figure shows representative results from three independent experiments. Line indicates the splice of two parts of the same filter aligned to one strip. (B) Immobilized peptides corresponding to proline-rich stretches in TSAd were probed with c-Src GST-SH3 domain fusion protein. Peptide sequences are shown to the right. The figure shows representative results from three independent experiments. Line indicates the splice of two parts of the same filter aligned to one strip. (C) Schematic representation of VEGFR2, TSAd, and c-Src molecular interactions.
Article Snippet: Peptide array membranes were probed with
Techniques: Phospho-proteomics, Sequencing, Stripping Membranes